4-Morpholinecarboxylic acid, 3-(aMinoMethyl)-, 1,1-diMethylethyl ester, (3S)- - Names and Identifiers
Name | tert-Butyl-(3S)-3-(aminomethyl)morpholin-4-carboxylat
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Synonyms | (S)-4-Boc-3-Aminomethylmorpholine (S)-4-BOC-3-AMINOMETHYL-MORPHOLINE (3S)-3-(Aminomethyl)-4-N-Boc-morpholine tert-Butyl-(3S)-3-(aminomethyl)morpholin-4-carboxylat (S)-tert-Butyl 3-(aMinoMethyl)Morpholine-4-carboxylate tert-Butyl (S)-3-(aminomethyl)morpholine-4-carboxylate tert-butyl (3S)-3-(aminomethyl)morpholine-4-carboxylate tert-Butyl (3S)-3-(aminomethyl)morpholine-4-carboxylate (S)-3-Aminomethyl-morpholine-4-carboxylic acid tert-butyl ester (S)-3-AMINOMETHYL-MORPHOLINE-4-CARBOXYLIC ACID TERT-BUTYL ESTER 4-Morpholinecarboxylic acid, 3-(aMinoMethyl)-, 1,1-diMethylethyl ester, (3S)- 4-morpholinecarboxylic acid, 3-(aminomethyl)-, 1,1-dimethylethyl ester, (3S)-
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CAS | 1187929-79-8
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InChI | InChI=1S/C10H20N2O3/c1-10(2,3)15-9(13)12-4-5-14-7-8(12)6-11/h8H,4-7,11H2,1-3H3/t8-/m0/s1 |
4-Morpholinecarboxylic acid, 3-(aMinoMethyl)-, 1,1-diMethylethyl ester, (3S)- - Physico-chemical Properties
Molecular Formula | C10H20N2O3
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Molar Mass | 216.28 |
Density | 1.078 |
Boling Point | 311℃ |
Flash Point | 142℃ |
pKa | 10.01±0.29(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
4-Morpholinecarboxylic acid, 3-(aMinoMethyl)-, 1,1-diMethylethyl ester, (3S)- - Introduction
(S)-4-Boc-3-(aminomethyl) morpholine is a pharmaceutical intermediate. The following is an introduction to its nature, use, preparation and safety information:
Nature:
(S)-4-Boc-3-(aminomethyl) morpholine is a solid with a molecular formula of C11H22N2O2 and a molecular weight of 214.3. It is a white crystalline or powdery substance, soluble in some organic solvents such as dimethyl sulfoxide and ethanol. It is stable at room temperature.
Use:
(S)-4-Boc-3-(aminomethyl) morpholine is often used as an intermediate in drug synthesis. It can be used to synthesize biologically active compounds such as potential drug molecules and hand emulsions.
Preparation Method:
A common preparation method is to react (S)-4-propoxycarbonyl-3-aminomorpholine with tert-butyl diisopropyl carbamate to produce (S)-4-Boc-3-(aminomethyl) morpholine. The reaction is generally carried out under an inert atmosphere at room temperature or under heating.
Safety Information:
(S)-4-Boc-3-(aminomethyl) morpholine has high safety, but it is still necessary to pay attention to operation safety. Avoid contact with skin and eyes, such as inadvertent contact, should immediately rinse with plenty of water. Wear protective gloves, glasses and laboratory coats during use. Safety regulations for chemicals should be followed during storage and handling.
Last Update:2024-04-09 02:00:41